SGPT Blood Test
An SGPT blood test is a test used to measure the amount of the enzyme glutamate pyruvate transaminase (GPT) in blood serum.
Significance of the SGPT Blood Test
This enzyme is found in the cells of heart, muscles, kidneys and pancreas only in small amounts but in much greater concentration in the liver. This test is also sometimes known as ALT or liver function test, where it is also combined with several other tests to find out how well the liver is functioning.
Benefits of SGPT Blood Test
An SGPT test is conducted to check if the liver is diseased or damaged and not functioning well. Normally, there is a low level of GPT in the blood serum but it gets raised in the presence of certain diseases such as hepatitis and cirrhosis. The use of certain medications like statins (to lower cholesterol) can also irritate the liver and causes GPT to be released in the blood. Early detection of elevated GPT levels in patients on statins can let the doctor know when to bring down or eliminate the use of that drug to prevent permanent damage to the liver.
Features of SGPT Lab Test
Normal results of SGPT test can vary from one lab to another. Each lab performing the SGPT test will print its normal values on the lab report. Most labs consider a GPT level from zero to 30 units per litre. The levels may be elevated considerably if the person to be tested drink too much alcohol or have chronic liver disease, gallstones, gallbladder disease or certain types of cancer. No known medical condition causes a person to have extremely low GPT levels.
Normal SGPT Lab Test Results
The normal range of values SGPT is from 7 to 56 units per litre of serum.
The highest levels are found with disorders that can kill liver cells in huge numbers. This occurs in conditions such as acute viral hepatitis A/B, overdose of acetaminophen (paracetamol) and prolonged dysfunctioning of the circulatory system, when the liver gets deprived of oxygen and blood. In such cases GPT serum levels could range from ten times the upper limit to thousands of units per litre.
Normally, mild to medium increase in these enzymes is considered widespread. The most common cause for this can be a fatty liver because of obesity, diabetes and excessive consumption of alcohol.
It is advisable to test the level of SGPT regularly through a preventive health checkup to see if it is increasing or remaining stable.